AREA OF INTEREST

• Infectious Diseases-Malaria, Haemophilus Influenzae, Rotavirus, Streptococcus Pnuemoniae, Rubella, Typhoid and Non-Typhoid Salmonellosis
• Hematology-Sickle Cell Disease
• Birth Defect Surveillance
• Non-Communicable Disease-Hypertension
• Poisons in Children

AREA OF SPECIALTY

• Child Health
• Epidemiology and Biostatistics
• Infectious Disease
• Human Psychology

RESEARCH INTEREST

• Infectious Disease
• Non Communicable Diseases
• Research Capacity Building
• Sickle Cell Disease

INSTITUTIONS ATTENDED

• Kwame Nkrumah University of Science and Technology, School of Medical Sciences
• University of Witwatersrand, Johannesburg, South Africa

QUALIFICATIONS

• BSc
• MB ChB
• FWCP
• FGCP
• MSc Epidemiology & Biostatistics
• Dip LTA (Learning Teaching and Assessment)

EMPLOYMENT & POSITION HELD/HOLD

• Associate Professor: Department of Paediatrics, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. August 2014-to date
• Deputy Director: Research and Development Unit, Komfo Anokye Teaching Hospital, Kumasi. January 2011 to date
• Senior Lecturer: Department of Paediatrics, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. February 2008-July 2014
• Lead Clinician: WHO/AFRO Invasive Bacterial Vaccine Preventable Disease (IBVPD) Surveillance Programme in the Department of Child Health, Komfo Anokye Teaching Hospital, Kumasi, Ghana. October 2002 to date
• Programme Coordinator: Long Distance Programme: Collaboration between Komfo Anokye Teaching Hospital (KATH) and Liverpool School of Tropical Medicine (LSTM) Diploma in Project Design and Management DPDM. April 2004 to date

ASSOCIATIONS/AFFILIATIONS

• Member of the Pediatrics Society of Ghana

HONOURS, AWARDS & ACHIEVEMENTS

• World Health Organization (WHO) Tropical Disease Research (TDR) Fellowship in Epidemiology and Biostatistics

PROFESSIONAL / TEACHING EXPERIENCE

• Lecturer in Child Health
• Facilitator and Coordinator of the Diploma in Project Management and Design (DPDM) -Liverpool of School Tropical Medicine (LSTM) Long Disease Program, based in Komfo Anokye Hospital, Kumasi, Ghana

PUBLICATIONS

• Kremsner PG, Adegnika AA, Hounkpatin AB, Zinsou JF, Taylor TE, Chimalizeni Y, et al. Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial. PLoS Med. 2016;13(1):e1001938–e1001938.
• Boadu NY, Amuasi J, Ansong D, Einsiedel E, Menon D, Yanow SK. Challenges with implementing malaria rapid diagnostic tests at primary care facilities in a Ghanaian district: a qualitative study. Malar J. 2016;15(1):1.
• Armah G, Pringle K, Enweronu-Laryea CC, Ansong D, Mwenda JM, Diamenu SK, et al. Impact and Effectiveness of Monovalent Rotavirus Vaccine Against Severe Rotavirus Diarrhea in Ghana. Clin Infect Dis. 2016;62(suppl 2):S200–S207.
• Ansong D, Nkyi C, Appiah CO, Amuzu EX, Frimpong CA, Nyanor I, et al. Epidemiology of paediatric poisoning reporting to a tertiary hospital in Ghana. South Afr J Child Health. 2016;10(1):68–70.
• White MT, Verity R, Griffin JT, Asante KP, Owusu-Agyei S, Greenwood B, et al. Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial. Lancet Infect Dis. 2015 Dec;15(12):1450–8.
• RTS,S Clinical Trials Partnership. Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. Lancet Lond Engl. 2015 Jul 4;386(9988):31–45.
• Neafsey DE, Juraska M, Bedford T, Benkeser D, Valim C, Griggs A, et al. Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine. N Engl J Med. 2015 Nov 19;373(21):2025–37
• Poyer S, Shewchuk T, Tougher S, Ye Y, Mann AG, Willey BA, Ansong D, et al. Availability and price of malaria rapid diagnostic tests in the public and private health sectors in 2011: results from 10 nationally representative cross-sectional retail surveys. Trop Med Int Health. 2015;20(6):744–56.
• Willey BA, Tougher S, Ye Y, ACTwatchGroup, Mann AG, Thomson R, Ansong D, et al. Communicating the AMFm message: exploring the effect of communication and training interventions on private for-profit provider awareness and knowledge related to a multi-country anti-malarial subsidy intervention. Malar J. 2014;13:46.
• RTS,S Clinical Trials Partnership. Efficacy and safety of the RTS,S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young infants at 11 African sites. PLoS Med. 2014 Jul 29;11(7):e1001685. doi: 10.1371/journal.pmed.1001685.
• Dunn A, Ansong D, Mvere D, Ansah J, Owusu-Ofori S, Gomo E, et al. T-REC: Strengthening capacity for blood transfusion research in Ghana and Zimbabwe. Afr Sang. 2014;16(2):14–8.
• Tougher S, Mann AG; ACTwatch Group, Ye Y, Kourgueni IA, Thomson R, Amuasi JH, Ren R, Willey BA, Ansong D, Bruxvoort K, Diap G, Festo C, Johanes B, Kalolella A, Mallam O, Mberu B, Ndiaye S, Nguah SB, Seydou M, Taylor M, Wamukoya M, Arnold F, Hanson K, Goodman C. Improving access to malaria medicine through private-sector subsidies in seven african countries. Health Aff (Millwood). 2014 Sep 1;33(9):1576-85. doi: 10.1377/hlthaff.2014.0104.
• White MT, Bejon P, Olotu A, Griffin JT, Bojang K, Lusingu J, Salim N, Abdulla S, Otsyula N, Agnandji ST, Lell B, Asante K, Owusu-Agyei S, Mahama E, Agbenyega T, Ansong D, Sacarlal J, Aponte JJ, Ghani AC. A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine.. BMC Med. 2014 Jul 10;12(1):117.
• Handlogten KS, Molitor RJ, Roeker LE, Narla NP, Bachman MJ, Quayson S, Owusu-Afriyie O, Adjei E, Ankobea F, Clayton A, Roberts L, MacLaughlin K, Ansong D. Cervical cancer screening in Ghana, west Africa: prevalence of abnormal cytology and challenges for expanding screening. Int J Gynecol Pathol. 2014 Mar;33(2):197-202. doi: 10.1097/PGP.0b013e318298a9e6.
• Rolling T, Agbenyega T, Issifou S, Adegnika AA, Sylverken J, Spahlinger D, Ansong D, Löhr SJ, Burchard GD, May J, Mordmüller B, Krishna S, Kremsner PG, Cramer JP. Delayed hemolysis after treatment with parenteral artesunate in African children with severe malaria--a double-center prospective study.. J Infect Dis. 2014 Jun 15;209(12):1921-8. doi: 10.1093/infdis/jit841.
• Ansong D, Osei-Akoto A, Ocloo D, Ohene-Frempong KO-F. Sickle Cell Disease: Management options and challenges in developing countries. Mediterr J Hematol Infect Dis. 2013 Nov 4;5(1):e2013062.
• Ansong D, Osei-Akoto A, Owusu SK, Boakye I, Nguah SB, Sambian DJ, Sylverken J, Arhin B. Haematological indices, nutritional assessment and mortality outcome of children presenting with severe malaria to a tertiary hospital in Ghana. Journal of Pediatric Sciences. 2013;5:e189
• Willardson SL, Dickerson TT, Wilson JS, Ansong D, Bueler E, Boakye I, Marfo J, Arhin B and Alder SC. Forming a Supplement Intervention Using a Multi Theoretical Behavior Model.Am J Health Behav. 2013;37(6):831-840 DOI: http://dx.doi.org/10.5993/AJHB.37.6.12
• Versporten A, Sharland M, Bielicki J, Drapier N, Vankerckhoven V, Goossens H; ARPEC Project Group Members. The antibiotic resistance and prescribing in European Children project: a neonatal and pediatric antimicrobial web-based point prevalence survey in 73 hospitals worldwide. Pediatr Infect Dis J. 2013 Jun;32(6):e242–253.
• Arnold M, VanDerslice JA, Taylor B, Benson S, Allen S, Johnson M, Kiefer J, Boakye I, Arhinn B, Crookston BT, Ansong D. Drinking water quality and source reliability in rural Ashanti region, Ghana. J Water Health. 2013 Mar;11(1):161–72
• RTS,S Clinical Trials Partnership, Agnandji ST, Lell BGesase S, , Ansong D, Agbenyega T, Adjei S, Boateng HO, Rettig T, Bawa J, Sylverken J, Sambian D, Sarfo A, Olivier A, Vekemans J, Carter T, Kaslow D, Leboulleux D, Loucq C, Radford A, Savarese B, Schellenberg D, Sillman M, Vansadia P. A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants. N. Engl. J. Med. 2012 Dec 13;367(24):2284–95.
• Tougher S; ACTwatch Group, Ye Y, Amuasi JH, Kourgueni IA, Thomson R, Goodman C, Mann AG, Ren R, Willey BA, Adegoke CA, Amin A, Ansong D, Bruxvoort K, Diallo DA, Diap G, Festo C, Johanes B, Juma E, Kalolella A, Malam O, Mberu B, Ndiaye S, Nguah SB, Seydou M, Taylor M, Rueda ST, Wamukoya M, Arnold F, Hanson K. Effect of the Affordable Medicines Facility--malaria (AMFm) on the availability, price, and market share of quality-assured artemisinin-based combination therapies in seven countries: a before-and-after analysis of outlet survey data. Lancet. 2012 Dec 1;380(9857):1916–26.
• Timmann C, Thye T, Vens M, Evans J, May J, Ehmen C, Sievertsen J, Muntau B, Ruge G, Loag W, Ansong D, Antwi S, Asafo-Adjei E, Nguah SB, Kwakye KO, Akoto AO, Sylverken J, Brendel M, Schuldt K, Loley C, Franke A, Meyer CG, Agbenyega T, Ziegler A, Horstmann RD. Genome-wide association study indicates two novel resistance loci for severe malaria. Nature. 2012 Sep 20;489(7416):443–6.
• Agnandji ST, Lell B, Soulanoudjingar SS, Fernandes JF, O, Kilavo H, Mahende C, Liheluka E, Lemnge M, Theander T, Drakeley C,Ansong D, Agbenyega T, Adjei S, Radford A, Savarese B, Schellenberg D, Sillman M, Vansadia P; RTS,S Clinical Trials Partnership. First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children. N. Engl. J. Med. 2011 Nov 17;365(20):1863–75.
• Swysen C, Vekemans J, Bruls M, Oyakhirome S, Drakeley C, Kremsner P, Greenwood B, Ofori-Anyinam O, Okech B, Villafana T, Carter T, Savarese B, Duse A, Reijman A, Ingram C, Frean J, Ogutu B; Clinical Trials Partnership Committee. Development of standardized laboratory methods and quality processes for a phase III study of the RTS, S/AS01 candidate malaria vaccine.Malar J. 2011 Aug 4;10:223
• Vekemans J, Marsh K, Greenwood B, Leach A, Kabore W, Soulanoudjingar S, Asante KP, Ansong D, Evans J, Sacarlal J, Bejon P, Kamthunzi P, Salim N, Njuguna P, Hamel MJ, Otieno W, Gesase S, Schellenberg D; Clinical Trials Partnership Committee. Assessment of severe malaria in a multicenter, phase III, RTS, S/AS01 malaria candidate vaccine trial: case definition, standardization of data collection and patient care. Malar. J. 2011;10:221.
• Swysen C, Vekemans J, Bruls M, Oyakhirome S, Drakeley C, Kremsner P, Greenwood B, Ofori-Anyinam O, Okech B, Villafana T, Carter T, Savarese B, Duse A, Reijman A, Ingram C, Frean J, Ogutu B; Clinical Trials Partnership Committee. Development of standardized laboratory methods and quality processes for a phase III study of the RTS, S/AS01 candidate malaria vaccine. Malar. J. 2011;10:223.
• Bates I, Taegtmeyer M, Squire SB, Ansong D, Nhlema-Simwaka B, Baba A, et al. Indicators of sustainable capacity building for health research: analysis of four African case studies. Health Res Policy Syst. 2011;9:14.
• Ansong D, Alder SC, Crookston BT, Beck C, Gyampomah T, et al. (2011) Role of Diagnostic Testing in Schistosomiasis Control Programs in Rural Ghana. J Bacteriol Parasitol 2:115. doi:10.4172/2155-9597.1000115
• Ansong D, Asante KP, Vekemans J, Owusu SK, Owusu R, Brobby NAW, et al. T cell responses to the RTS,S/AS01(E) and RTS,S/AS02(D) malaria candidate vaccines administered according to different schedules to Ghanaian children. PLoS ONE. 2011;6(4):e18891
• Dondorp AM, Fanello CI, Hendriksen IC, Gomes E, Seni A, Chhaganlal KD, Bojang K, Olaosebikan R, Anunobi N, Maitland K, Kivaya E, Agbenyega T, Nguah SB, Evans J, Gesase S, Kahabuka C, Mtove G, Nadjm B, Deen J, Mwanga-Amumpaire J, Stepniewska K, Woodrow CJ, Bethell D, Wills B, Oneko M, Peto TE, von Seidlein L, Day NP, White NJ; AQUAMAT group. Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial. Lancet. 2010 Nov 13;376(9753):1647–57.
• Schuldt K, Esser C, Evans J, May J, Timmann C, Ehmen C, Loag W, Ansong D, Ziegler A, Agbenyega T, Meyer CG, Horstmann RD. FCGR2A functional genetic variant associated with susceptibility to severe malarial anaemia in Ghanaian children. J. Med. Genet. 2010 Jul;47(7):471–5.
• Owusu-Agyei S, Ansong D, Asante K, Kwarteng Owusu S, Owusu R, Wireko Brobby NA, et al. Randomized controlled trial of RTS,S/AS02D and RTS,S/AS01E malaria candidate vaccines given according to different schedules in Ghanaian children. PLoS ONE. 2009;4(10):e7302.
• Moorthy V, Reed Z, Smith PG; WHO Study Group on Measures of Malaria Vaccine Efficacy. Measurement of malaria vaccine efficacy in phase III trials: report of a WHO consultation. Vaccine. 2007 9;25(28):5115-23.
• Taylor T, Olola C, Valim C, Agbenyega T, Kremsner P, Krishna S, Kwiatkowski D, Newton C, Missinou M, Pinder M, Wypij D. Standardized data collection for multi-center clinical studies of severe malaria in African children: establishing the SMAC network. Trans R Soc Trop Med Hyg. 2006 Jul;100(7):615-22.
• Olola CH, Missinou MA, Issifou S, Anane-Sarpong E, AbubakariI, Gandi JN, Chagomerana M, Pinder M, Agbenyega T, Kremsner PG, Newton CR, Wypij D, Taylor TE: SMAC Network. Medical informatics in medical research-the Severe Malaria in African Children (SMAC) Networks experience. Methods Inf Med. 2006; 45(5)_483-91.
• Co-Principal Investigator: Phase III randomized, open, controlled study to evaluate the immune response to the hepatitis B antigen of the RTS,S/AS01E candidate vaccine, when administered as primary vaccination integrated into an EPI regimen to infants living in sub-Saharan Africa. June 2012 to date
• Principal Investigator: Multiple Micronutrient Study in women living in the Barekese sub-district of the Ashanti Region. An International Collaboration with University of Utah-United States of America (USA), Kirk Humanitarian-USA and Kwame Nkrumah University of Science and Technology. August 2013 to date
• Co-Principal Investigator: Phase 3 double-blind, randomized efficacy and safety comparison of prasugrel and placebo in pediatric patients with sickle cell disease. April 2014 to date
• Principal Investigator: Training mothers and caregivers to recognise the early clinical signs of pneumonia in children less than 2 years in ghana: proof of concept study. July 2016 to date