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Research & Outreach Activities Department of Medicine

HIV: Currently HIV is being studied intensive covering prospective treatment studies, diagnostic assays coinfection with hepatitis B, pharmacokinetics and phamacogenetics. One of these studies involve A prospective study investigating the  pharmacokinetic interaction between efavirenz and artemisinin-based antimalarial drugs in Ghanaian HIV infected patients.

BURULI ULCER: Studies into Buruli ulcer have been ongoing since 1996 covering areas such as development of diagnostic assays, immunopathogenesis, treatment modalities, control activities. Some of the ongoing studies involve

  • A study of the response of pre-ulcerative and early ulcerative lesions caused by M. ulcerans to 8 weeks treatment of daily combination of Streptomycin and Rifampicin or Clarithromycin and Rifampicin is being carried out in the Ahafo Ano North District.  This is aimed at developing an oral regimen for treating Buruli ulcer.
  • In collaboration with the World Health Organisation and the Ahafo Ano North District colleagues in the department are carrying out an outreach education and treatment programme in the Ahafo Ano North District title “Early detection diagnosis and treatment of Buruli ulcer in Ahafo Ano North District, Ghana”

MALARIA: Cardiovascular Failure in Severe Malaria

DIABETES MELLITUS: Prevalence of diabetic nephropathy in patients attending the diabetic clinic at Komfo Anokye Teaching hospital, Kumasi, Ghana.

GASTROENTEROLOGY: Endoscopic findings in patients with upper GIT bleeding at KATH

STROKE: Association between serum uric acid levels and outcomes types and risk factors of stroke at KATH

Other topics being investigated include tuberculosis, hepatitis B and C infection, Chronic Myeloid leukemia