AREA OF INTEREST

• Neurology
• Infectious Diseases

AREA OF SPECIALTY

• INTERNAL MEDICINE
• MOLECULAR MEDICINE

RESEARCH INTEREST

• Stroke and Neurological Disorders- clinical, epidemiology, molecular determinants
• Buruli ulcer Disease- pathogenesis, diagnostics and treatment
• HIV – treatment outcomes, co-infections, pharmacology
• Hepatitis B, C, D and E

INSTITUTIONS ATTENDED

• Kwame Nkrumah University of Science & Technology
• Durham University, United Kingdom
• West African College of Physicians

QUALIFICATIONS

• PhD (2013)
• PhD (2012)
• FWACP
• MWACP
• MBChB
• BSc

EMPLOYMENT & POSITION HELD/HOLD

• Senior Lecturer, School of Medical Sciences
• Senior Specialist Physician, Komfo Anokye Teaching Hospital
• Kwame Nkrumah University of Science & Technology
• Komfo Anokye Teaching Hospital

ASSOCIATIONS/AFFILIATIONS

• Ghana Medical Association
• West Africa College of Physicians – Secretary for Internal Medicine, Ghana Chapter

HONOURS, AWARDS & ACHIEVEMENTS

• Best Doctor Award, 2010
• Setting up a stroke unit at Komfo Anokye Teaching Hospital

PROFESSIONAL / TEACHING EXPERIENCE

• Senior Specialist Physician
• Senior Lecturer

PUBLICATIONS

• Sarfo FS, Sarfo MA, Norman B, Phillips R, Bedu-Addo G, Chadwick D. Risk of deaths, AIDS-defining and non-AIDS defining events among Ghanaians on long-term antiretroviral therapy. PLoS ONE. 2014. 
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• Layden JE, Phillips RO, Owusu-Ofori S, Sarfo FS, Kliethermes S, Mora Nallely, Owusu D, Nelson K, Opare-Sem O, Dugas L, Luke A, Shoham D, Forbi JC, Khudyakov YE, Cooper RS. High frequency of active HCV infection among seropositives in West Africa and evidence for multiple transmission pathways. Clin. Infect. Dis. 2014. 
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• Phillips RO, Phanzu DM, Beisnner M, Badziklou K, Luzolo EK, Sarfo FS, Halatoko WA, Amoako Y, Frimpong M, Kabiru AM, et al., Effectiveness of routine BCG vaccination on Buruli Ulcer Disease: a case-control study in the Democratic Republic of Congo, Ghana and Togo. PLoS NTD 2014. 
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• King S, Adjei-Asante K, Appiah L, Adinku D, Beloukas A, Atkins M, Sarfo FS, Chadwick D, Phillips RO, Geretti AM. Antibody screening tests variably overestimate the prevalence of hepatitis C virus infection among HIV-infected adults in Ghana. Journal of Viral Hepatitis 2014. 
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• Phillips R, Sarfo F, Abass K, Frimpong M, Ampadu E, Forson M, Ampem-Amoako Y, Thompson W, Kingsley, Asiedu KB, and Wansbrough-Jones M. Compliance with Antimicrobial Therapy for Buruli Ulcer. AAC03874-14. 
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• Abass K, van der Werf T, Phillips R, Sarfo FS, Abotsi J, Mireku S, Thompson William, Asiedu K, Stienstra Y, Klis SA. Buruli ulcer control in a highly endemic district in Ghana: role of community-based surveillance volunteers. AJTMH-14-0405. 
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• The H3 Africa Consortium*. Enabling the genomic revolution in Africa. Science 2014 Jun 20;344 (6190):1346-1348. 
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• Sarfo FS, Sarfo MA, Norman B, Phillips R, Chadwick D. Incidence and determinants of nevirapine and efavirenz-related skin rashes in West Africans: Nevirapine’s epitaph? PLoS One. 2014 Apr 11;9(4):e94854. 
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• Sarfo FS, Kassim A, Phillips R, Geretti AM, Chadwick DR. Long-term responses to first-line antiretroviral therapy in HIV and hepatitis B co-infection in Ghana. Journal of Infection YJINF-D-14-00081 (accept). 
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• Cilia R, Akpalu A, Sarfo FS, Cham M, Amboni M, Cereda E, Fabbri M, Patrick A, Akassi J, Bonetti A, Pezzoli G. The Modern pre-Levodoap Era of Parkinson’s Disease: Insights into Motor Complications from sub-Saharan Africa. Brain-2014-00507 (accept). 
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• Sarfo FS, Phillips RO, Zhang J, Abass MK, Abotsi J, Amoako YA, Adu-Sarkodie Y, Robinson C, Wansbrough-Jones MH. Kinetics of mycolactone in human subcutaneous tissue during antibiotic therapy for Mycobacterium ulcerans disease. BMC Infect Dis. 2014 Apr 15;14:202. 
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• Phillips RO, Sarfo FS, Landier J, Oldenburg R, Wansbrough-Jones M, Kabiru A, Thompson W, Forson M, Fontanet A, Fatoumata N, Demangel C. Combined inflammatory and metabolic defects reflected by reduced serum protein levels in patients with Buruli ulcer disease. PLoS Negl Trop Dis. 2014 Apr 10;8(4):e2786. 
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• Phillips RO, Frimpong M, Sarfo FS, Birte Kretschmer, Marcus Beissner, Amoako Y, Debrah A, Abass K M, Thompson W, Sarpong Duah M, Ohene-Adjei, Fleischer B, Bretzel G, Wansbrough-Jones M, Jacobssen M. Co-infection with Mycobacterium ulcerans and Mansonella perstans among Buruli ulcers in Ghana. Emerg Infect Dis. 2014 Jun;20(6):1000-3. 
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• Sarfo FS, Thompson W, Phillips RO, Paintsil A, Abass MK, Frimpong M, Abotsi J, Kingsley A, Wansbrough-Jones MH. A Severe Case of Buruli Ulcer Disease with Pleural Effusions. PLoS Negl Trop Dis. 2014; 8(6): e2868. 
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• Moritz Jansson, Marcus Beissner, Richard Phillips, Kossi Badziklou, Ebekalisai Piten, Issaka Maman, Sarfo FS, Kristina Huber, Agata Rhomberg, Dominik Symank, Magdalena Wagner, Franz Wiedemann, Jörg Nitschke, Abiba Banla Kere, Karl-Heinz Herbinger, Ohene Adjei, Thomas Löscher, and Gisela Bretzel. Molecular Determination of Rifampicin Resistance in Clinical Samples of Patients with Buruli Ulcer Disease: A Comparison of two Assays. J Clin Microbiol. 2014 Apr;52(4):1246-9. 
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• Williamson HR, Phillips R, Sarfo S, Wansbrough-Jones M, Small PLC. Genetic diversity of PCR-positive, culture-negative and culture-positive Mycobacterium ulcerans isolated from Buruli ulcer patients in Ghana. PLoS ONE 9(2): e88007 
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• Sandor K, van der Werf TS, Phillips RO, Sarfo FS, Wansbrough-Jones M, Stienstra Y. Oral treatment for patients with Buruli ulcer co-infection with HIV: think twice. AIDS 2013 Correspondence. 
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• Phillips RO, Sarfo FS, Abass MK, Abotsi J, Tuah W, Forson M, Amoako YA, Thompson W, Asiedu K, Wansbrough-Jones M: Clinical and bacteriological efficacy of combination of rifampicin and streptomycin for 2 weeks followed by rifampicin and clarithromycin for 6 weeks for treatment of Mycobacterium ulcerans disease. Antimicrob Agents Chemother. 2014 Feb;58(2):1161-6. doi: 10.1128/AAC.02165-13. Epub 2013 Dec 9. Erratum in: Antimicrob Agents Chemother. 2014 Apr;58(4):2488. 
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• Kollie K, Amoako YA, Ake J, Mulbah T, Zaizay F, Abass M, Lehman L, Paintsil A, Sarfo F, Lugala C, Tiendrebeogo A, Phillips R, Asiedu K. Buruli ulcer in Liberia, 2012. Emerg Infect Dis. 2014 Mar; 20(3): 494-6. 
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• Sarfo FS, Sarfo MA, Kasim A, Phillips R, Booth M, Chadwick D. Long-term effectiveness of first-line non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral therapy in Ghana. J Antimicrob Chemother. 2014;69(1):254-61.
• Sarfo FS, Zhang Y, Egan D, Tetteh LA, Phillips R, Bedu-Addo G, Sarfo MA, Khoo S, Owen A, Chadwick D. Pharmacogenetic associations with plasma efavirenz concentrations and clinical correlates in a retrospective cohort of Ghanaian HIV-infected patients. J Antimicrob Chemother. 2014;69(2):491-9. 
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• Sarfo FS, Acheampong JW, Tetteh LA, Oparebea E, Akpalu A, Bedu-Addo G. The profile of risk factors and in-patient outcomes of stroke in Kumasi, Ghana. 2013 Ghana Medical Journal, GMJ-2013-01-007 (accept) 
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• Feldt T, Sarfo FS, Zoufaly A, Phillips RO, Burchard G, van Lunzen J, Jochum J, Chadwick D, Awasom C, Claussen L, Drosten C, Drexler JF, Els-Hubinger AM. Hepatitis E virus infections in HIV-infected patients in Ghana and Cameroun. J Clin Virol. 2013 Sep;58(1):18-23. 
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• Sarfo FS, Keegan R, Appiah L, Shakoor S, Phillips R, Norman B, Hardy Y, Bedu-Addo G, Longstaff L, Chadwick DR. High prevalence of renal dysfunction and association with risk of death amongst HIV-infected Ghanaians. J Infect. 2013 Jul; 67(1):43-50. 
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• Sarfo FS, Converse PJ, Almeida DV, Zhang J, Robinson C, Wansbrough-Jones M, Grosset JH. Microbiological, Histological, Immunological, and Toxin Response to Antibiotic Treatment in the Mouse Model of Mycobacterium ulcerans Disease. PLoS Negl Trop Dis. 2013; 7(3): e2101. 
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• Chadwick D, Stanley A, Sarfo S, Appiah L, Ankcron M, Foster G, Schwab U, Phillips R, Geretti AM. Response to antiretroviral therapy in occult hepatitis B and HIV co-infection in West Africa. AIDS. 2013 Jan 2;27(1):139-41. 
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• Chadwick D, Ankcorn M, Sarfo FS, Phillips R, Fox Z, Garcia A, Appiah L, Bedu-Addo G, Geretti AM. Outcomes of starting first-line antiretroviral therapy in hepatitis B virus/HIV-coinfected patients in Ghana. J Antimicrob Chemother 2012 Dec;67(12):2939-42. 
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• Mamoojee Y, Tan G, Gittins S, Sarfo FS, Stephenson L, Carrington D, Bedu-Addo G, Phillips R, Appiah LT, Chadwick D. Diagnosis of treponemal co-infection in HIV-infected West Africans. Trop Med Int Health. 2012 Sep 20. Doi: 10.1111/j.1365-3156.2012.03090.x. 
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• Beissner M, Symank D, Phillips RO, Amoako YA, Awua-Boateng NY, Sarfo FS, Jansson M, Huber KL, Herbinger KH, Battke F, Loscher T, Ohene Adjei, Bretzel G. Detection of viable Mycobacterium ulcerans in clinical samples by a novel combined 16S rRNA reverse transcriptase/IS2404 real-time qPCR assay. PLoS Negl Trop Dis. 2012; 6(8): e1756. 
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• Sarfo FS, Le Chevalier F, Aka N, Phillips RO, Amoako Y, Boneca IG, Lenormand P, Dosso M, Wansbrough-Jones M, Veyron-Churlet R, Guenin-Mace L, Demangel C. Mycolactone diffuses into the peripheral blood of Buruli ulcer patients-Implications for Diagnosis and Disease Monitoring. PLoS Negl Trop Dis. 2011 Jul; 5(7):e1237. 
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• Sarfo FS, Lavender CJ, Fyfe JAM, Johnson PDR, Stinear TP, Phillips R. Mycobacterium ulcerans DNA not detected in faecal samples from Buruli ulcer patients: results from a pilot study. PLoS One. 2011 May 4; 6(5): e19611.
• Cilia R, Sironi F, Akpalu A, Cham M, Sarfo FS, Brambilla T, Bonetti A, Amboni M, Goldwurm S, Pezzoli G. Screening LRRK2 gene mutations in patients with Parkinson’s disease in Ghana. J Neurol. 2012 Mar;259(3):569-70. 
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• Mamoojee Y, Shakoor S, Garton RL, Sarfo FS, Appiah LT, Norman B, Balakrishnan I, Phillips R, Chadwick D. Low seroprevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme in Ghana. Trop Med Int Health. 2011 Jan;16(1): 53-56. 
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• Geretti AM, Patel M, Sarfo FS, Chadwick D, Verheyen J, Fraune M, Garcia A, Phillips R. Detection of highly prevalent hepatitis B virus coinfection among HIV-seropositive persons in Ghana. J Clin Microbiol. 2010 Sep; 48(9): 3223-30. 
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• Sarfo FS, Phillips R, Asiedu KB, Ampadu E, Bobi N, Adentwe E, Lartey A, Tetteh I, Wansbrough-Jones M. Clinical efficacy of combination of rifampin and streptomycin for the treatment of Mycobacterium ulcerans disease. Antimicrob Agents Chemother. 2010 Sep;54(9):3678-3685 
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• Sarfo FS, Phillips RO, Rangers B, Mahrous EA, Lee RE, Tarelli E, Asiedu KB, Small PL, Wansbrough-Jones MH. Detection of Mycolactone A/B in Mycobacterium ulcerans -Infected Human Tissue. PLoS Negl Trop Dis. 2010 Jan 5;4(1): e577. 
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• Sarfo FS, Bibby DF, Schwab U, Tetteh LA, Clark DA, Collini P, Phillips R, Green I, Dittmar MT, Chadwick D. Inadvertent Non-nucleoside reverse transcriptase inhibitor based Anti-Retroviral Therapy in dual HIV 1 / 2 and HIV-2 seropositive West Africans: a retrospective study. J. Antimicrob. Chemother 2009 Sep 64(3): 667-9. 
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• Phillips R, Sarfo FS, Guenin-Mace L, Decalf J, Wansbrough-Jones M, Albert ML, Demangel C. Immunosuppressive signature of cutaneous Mycobacterium ulcerans infection in the peripheral blood of buruli ulcer patients. J Infect Dis. 2009 Dec 1;200(11):1675-84. 
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• Appiah L, Havers F, Gibson J, Kay M, Sarfo FS, Chadwick D. Efficacy and acceptability of rapid, point-of-care HIV testing in two clinical settings in Ghana. AIDS Patient Care and STD’s, 2009 May; 23 (5): 365-9. 
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• Phillips RO, Sarfo FS, Osei-Sarpong F, Boateng A, Tetteh I, Lartey A, Adentwe E, Opare W, Asiedu KB, Wansbrough-Jones M. Sensitivity of PCR targeting Mycobacterium ulcerans by use of fine-needle aspirates for diagnosis of Buruli ulcer. J Clin Microbiol. 2009 Apr: 47 (4): 924-6. 
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• Collini P, Schwab U, Sarfo FS, Obeng-Baah J, Norman B, Chadwick D, Bibby D, Bedu-Addo G. Sustained Immunological responses to HAART at 36 months in Ghanaian HIV cohort. Clin. Infect. Dis. 2009; Apr 1: 48(7): 988-91. 
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• Sarfo FS, Phillips RO, Ampadu E, Sarpong F, Adentwe E, Wansbrough-Jones M. Dynamics of the cytokine response to Mycobacterium ulcerans during antibiotic treatment for M. ulcerans disease (Buruli ulcer) in humans. Clinical and Vaccine Immunology 2009,p.61-65. 
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• Phillips R, Horsfield C, Kuijper S, Sarfo FS, Obeng-Baah J, Etuaful S, Nyamekye B, Awuah P, Nyarko KM, Osei-Sarpong F, Lucas S, Kolk AHJ and Wansbrough-Jones M. Cytokine response to antigen stimulation of whole blood from patients with Mycobacterium ulcerans disease compared to that from patients with tuberculosis. Clin Vaccine Immunol 2006;13(2):253-7. 
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