AREA OF INTEREST

• HCV infection
• HBV infection
• Tranfusion related problems

AREA OF SPECIALTY

• Haematology/Oncology

RESEARCH INTEREST

• Malaria
• Massive splenomegaly
• Diabetes Mellitus
• HIV

INSTITUTIONS ATTENDED

• Kwame Nkrumah University B.Sc. 1984 Human Biology
• University of Nottingham B.Med.Sc 1986 Physiology/Pharmacology
• Columbia Univ. College of Physicians & Surgeons ABIM 1994 Internal Medicine
• Univ of Med. & Dentistry of New Jersey ABIM 1997 Haematology/Oncology
• Haggai Institute Cert. 2006 Advanced Leadership

QUALIFICATIONS

• FWACP
• MB ChB
• BSc

EMPLOYMENT & POSITION HELD/HOLD

• ASSOCIATE PROFESSOR OF MEDICINE
• CONSULTANT HAEMATOLOGIST
• 1988-1991 House/Medical Officer, Komfo Anokye Teaching Hospital, Ghana
• 1989-1991 Assistant Lecturer, School of Medical Sciences, Univ. of Science and Technology, Ghana
• Resident Physician, Columbia Univ. College of Physicians and Surgeons at Harlem Hospital Hospital Centre, New York
• 1994-1997 Fellow, Divisions of Haematology and Oncology, Robert Wood Johnson Univ. Hospital and Cancer Institute of New Jersey, Brunswick

ASSOCIATIONS/AFFILIATIONS

• KNUST, UPO, KUMASI.

HONOURS, AWARDS & ACHIEVEMENTS

• I have, over the past 10 years, through institutional collaborations mentored both undergraduate and clinical Postgraduate trainees from University of Michigan, University of Utah, The University of Hamburg, among others in Internal Medicine, Haematology /Oncology .
• I have, over the past 10 years, through institutional collaborations mentored both undergraduate and clinical Postgraduate trainees from University of Michigan, University of Utah, The University of Hamburg, among others in Internal Medicine, Haematology /Oncology .
• My main interests have been in the clinical areas of Chronic Hepatitis B infections, Nucleic Acid Testing in Pre-Donation Screening Transfusion Medicine, and using platelet flow cytometry as a marker for platelet activation. My clinical work involves the treatment of a wide range of malignacies and haematological disorders. However, I have a keen and still growing, interest in medical education and lately Open Educational Resource (OER) in the health sciences that has culminated in my appointment as the Coordinator for OER activities in the College of Health Sciences. This has involved the drafting of a university wide policy, designing and operating an OER production/publishing system. I have mentored students at all levels, recently serving as a mentor for students in the Minority Health International Research Training Program. I am pleased to colloborate in this HBV study

PROFESSIONAL / TEACHING EXPERIENCE

• 1991 -  Certificate, United States Medical Licensure Examinations
• 1993 -  Certificate, United States Federal Licensing Board
• 1994 -  Diplomate, American Board of Internal Medicine
• 1994 -  Member, American College of Physicians
• 1997 -  Diplomate, American Subspecialty Board of Hematology
• 2000 -  Fellow, American College of Physicians
• 2008 -  Fellow, Royal College of Physicians, UK

PUBLICATIONS

• 1. Roberts, M., Opare-Sem, K. (1994) Acheampong J. The Diurnal Variation of Stroke in Ghana. Tropical Doctor, (24)155. 
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• 2. Rosenburg N., Murata M., Ikeda Y., Opare-Sem O., Zivelin A., Geffen E., Seligsohn U. (2002) The Frequent 5, 10-Methylene Tetrahydrofolate Reductase C677T Polymorphism is associated with a common haplotype in Whites, Japanese, and Africans. American Journal of Human Genetics, (70) 756-762. 
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• 3. Opare-Sem O., Owusu-Ofori S., Allain J-P. (2002) A novel approach to blood safety. Pre-donating screening of blood donors for viral markers. (Editorial) Africa Sanguine, (5)12-16. 
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• 4. Fischetti L., Opare-Sem O., Candotti D., Lee H., Allain J-P. (2004) Higher viral load may explain the dominance of CRF02_AG in the molecular epidemiology of HIV in Ghana. AIDS, (18) 1208-1210. 
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• 5. Fischetti L., Opare-Sem O., Candotti D., Sarkodie F., Lee H., Allain J-P. (2004) Molecular epidemiology of HIV in Ghana: Dominance of CRF02_AG. Journal of Medical Virology, (00)1-9. 
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• 6. Candotti D., Opare-Sem O., Rezvan H., Sarkodie F., Allain J-P. (2006) Molecular and serological characterization of hepatitis B virus in deferred Ghanaian blood donors with and without elevated alanine aminotransferase. Journal of Viral Hepatitis, (13)715-72. 
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• 7. Chengyao Li, Collini P., Danso K., Owusu-Ofori S., Dompreh A., Candotti D., Opare-Sem O., Allain J-P. (2006) GB virus C and HIV-1 RNA load in single virus and co-infected West African individuals. Aids, (20) 379-86. 
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• 8. Allain J-P., Sarkodie F., Candotti D., Opare-Sem O. (2005) Lack of correlation between hepatitis B surface antigen and hepatitis B virus DNA levels in blood donors. Transfusion, (45)1039-1040. 
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• 9. Allain J-P., Candotti D., Soldan K., Sarkodie F., Phelps B., Giachetti C., Yeboah F., Shyamala V., Anokwa M., Owusu-Ofori S., Opare-Sem O. (2003) The risk of hepatitis B virus infection by transfusion in Kumasi, Ghana. Blood, (101)2419-2425. 
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• 10. Evans D., Opare-Sem K., Kotoh S., Amon Kotei D. (1988) Is colorectal cancer risk increasing in Ghana? GMJ (22)8-16.
• 11. Layden JE, Phillips RO, Owusu-Ofori S, Sarfo FS, Kliethermes S, Mora N, Owusu D, Nelson K, Opare-Sem O, Dugas L, Luke A, Shoham D, Forbi JC, Khudyakov YE, Cooper RS. High Frequency of Active HCV Infection Among Seropositive Cases in West Africa and Evidence for Multiple Transmission Pathways. Clin Infect Dis.2014 Dec 4. pii: ciu965. [Epub ahead of print] PubMed PMID: 25477425. 
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• 12. Opare-Sem O, Bedu-Addo G, Karikari P, Boateng P, Sarkodie F, Rahman R,Asenso-Mensah K, Awuah B, Osei Akoto A, Munin SA, Mensah-Acheampong F, Allain JP, Owusu-Ofori S. Fourteen-year experience of a tertiary hospital transfusion committee in West Africa. Transfusion. 2014 Nov;54(11):2852-62. doi:10.1111/trf.12690. Epub 2014 May 20. PubMed PMID: 24845344. 
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• 13. Ala F, Allain JP, Bates I, Boukef K, Boulton F, Brandful J, Dax EM, El Ekiaby M, Farrugia A, Gorlin J, Hassall O, Lee H, Loua A, Maitland K, Mbanya D, Mukhtar Z, Murphy W, Opare-Sem O, Owusu-Ofori S, Reesink H, Roberts D, Torres O, Totoe G,Ullum H, Wendel S. External financial aid to blood transfusion services insub-Saharan Africa: a need for reflection. PLoS Med. 2012;9(9):e1001309. doi:10.1371/journal.pmed.1001309. Epub 2012 Sep 11. PubMed PMID: 22984355; PubMed Central PMCID: PMC3439367.
• 14. Adanu R, Adu-Sarkodie Y, Opare-Sem O, Nkyekyer K, Donkor P, Lawson A,Engleberg NC. Electronic learning and open educational resources in the health sciences in ghana. Ghana Med J. 2010 Dec;44(4):159-62. PubMed PMID: 21416051; PubMed Central PMCID: PMC3052833. 
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• 15. Compston LI, Li C, Sarkodie F, Owusu-Ofori S, Opare-Sem O, Allain JP.Prevalence of persistent and latent viruses in untreated patients infected withHIV-1 from Ghana, West Africa. J Med Virol. 2009 Nov;81(11):1860-8. doi:10.1002/jmv.21614. PubMed PMID: 19774687. 
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• 16. Allain JP, Opare-Sem O, Sarkodie F, Rahman R, Owusu-Ofori S. Deferred donorcare in a regional hospital blood center in Ghana. Transfusion. 2009Apr;49(4):669-75. doi: 10.1111/j.1537-2995.2008.02055.x. Epub 2008 Jan 2. PubMed PMID: 19170991. 
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• 17. Compston LI, Sarkobie F, Li C, Candotti D, Opare-Sem O, Allain JP. Multiplex real-time PCR for the detection and quantification of latent and persistent viral genomes in cellular or plasma blood fractions. J Virol Methods. 2008Jul;151(1):47-54. doi: 10.1016/j.jviromet.2008.03.023. Epub 2008 May 13. PubMedPMID: 18479760. 
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• 18. Odinsen O, Owusu-Ofori S, Dompreh A, Sarkodie F, Opare-Sem O, Parker D, AllainJP. Antibody detection and kinetics of antibody production during early stages of immunization with hepatitis B virus vaccine. Clin Vaccine Immunol. 2007 Dec;14(12):1623-8. Epub 2007 Oct 10. PubMed PMID: 17928429; PubMed Central PMCID: PMC2168390. 
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• 19. Jennifer E. Layden, Richard Phillips, Ohene Opare-Sem, Adegboyega Akere, Babatunde L. Salako, Kenrad Nelson, Lara Dugas, Amy Luke, Bamidele O. Tayo, and Richard S. Cooper Hepatitis C in Sub-Saharan Africa: Urgent Need for Attention Open Forum Infect Dis (Summer 2014) 1 (2): doi:10.1093/ofid/ofu065 
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